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Category: 7TM ReceptorsarrowProstanoid Receptors
Cat.No. Product Name
0671 AH 6809  
Price and Availability

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AH 6809
Chemical Name: 6-Isopropoxy-9-xanthone-2-carboxylic acid

Biological Activity:

Antagonist at prostaglandin EP1 (pA2 = 6.8 ) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45).

Technical Data:

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M.Wt: 298.3
Formula: C17H14O5 
Storage: Store at RT
Solubility: Soluble to 100 mM in 1.1eq. NaOH
Purity: >99%
CAS No: [33458-93-4]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch
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    References:

    Coleman et al (1985) AH6809, a prostanoid EP1-receptor blocking drug. Br.J.Pharmacol. 85 273P. Keery and Lumley (1988) AH 6809, a prostaglandin DP-receptor blocking drug on human platelets. Br.J.Pharmacol. 94 745. Kiriyama et al (1997) Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br.J.Pharmacol. 122 217.
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    Keywords: AH 6809, Prostanoid Receptors, EP1 & EP2 Receptor Antagonist, AH6809, Tocris Bioscience

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