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Category:
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Nuclear Receptors Retinoic Acid Receptors
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Cat.No.
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Product Name
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2436 |
AC 55649
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Price and Availability
Click here for full price details of
AC 55649
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Chemical Name:
4'-Octyl-[1,1'-biphenyl]-4-carboxylic acid |
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Biological Activity:
Potent,
isoform-selective RARβ2 receptor agonist (pEC50
= 6.9) that displays 100-fold selectivity versus other retinoid receptors. Inhibits
proliferation of the breast cancer cell line MCF-7.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Lund et al (2005) Discovery of a
potent, orally available, and isoform-selective retinoic acid β2 receptor agonist. J.Med.Chem. 48
7517.
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or by Research Area
Keywords: AC 55649, Retinoic Acid Receptors, Selective RARb2 Agonist, AC55649, Tocris Bioscience
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