Melanocortin (MC) Receptors

More Information »Melanocortin receptors are activated by members of the melanocortin family: α-, β- and γ-melanocyte stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). The melanocortins are involved in a range of physiological functions, including pigmentation and inflammation.

Melanocortin (MC) Receptor Products

Agonists
Cat.No.	Product Name / Activity
3492	ACTH (1-39)
	Potent endogenous MC₂ agonist
4053	BMS 470539 dihydrochloride
	Potent, selective MC₁ receptor agonist
2566	Melanotan II
	High affinity melanocortin receptor agonist
3424	γ1-MSH
	Selective MC₃ receptor agonist
4272	[D-Trp⁸]-γ-MSH
	Selective MC₃ receptor agonist
2584	α-MSH
	Endogenous melanocortin receptor agonist
3013	[Nle⁴,D-Phe⁷]-α-MSH
	Melanocortin receptor agonist
3032	THIQ
	Potent and selective MC₄ receptor agonist
Antagonists
Cat.No.	Product Name / Activity
1831	HS 014
	Selective MC₄ receptor antagonist
1832	HS 024
	Highly potent MC₄ receptor antagonist
3426	JKC 363
	Potent and selective MC₄ receptor antagonist
3438	MCL 0020
	Selective MC₄ receptor antagonist
Other
Cat.No.	Product Name / Activity
3611	Lys-γ3-MSH
	Pro-opiomelanocortin (POMC) derived peptide
1929	Melanocyte stimulating hormone release inhibiting factor
	Inhibitor of α-MSH release; inhibits opioid effects in vivo
3420	SHU 9119
	MC₃ and MC₄ antagonist, MC₅ partial agonist

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