GTPase

More Information »GTPases are a group of enzymes that catalyze hydrolysis of the γ phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP). Mg²⁺ ions are essential for catalytic activity. GTPases, often coupled to G proteins, are essential in signal transduction.

GTPase Products

Inhibitors
Cat.No.	Product Name / Activity
1774	Dynamin inhibitory peptide
	Dynamin inhibitor
1775	Dynamin inhibitory peptide, myristoylated
	Cell-permeable dynamin inhibitor
1776	Dynamin inhibitory peptide, myristoylated (control)
	Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)
2897	Dynasore
	Non-competitive dynamin inhibitor
4222	Dynole 34-2
	Dynamin I inhibitor
3872	EHT 1864
	Potent inhibitor of Rac family GTPases
3584	Golgicide A
	Potent, specific and reversible inhibitor of GBF1 ArfGEF
3792	ITX 3
	Selective inhibitor of TrioN RhoGEF activity
3982	Mdivi 1
	Dynamin inhibitor; attenuates mitochondrial division and apoptosis
4224	MitMAB
	Dynamin inhibitor
4266	ML 141
	Selective inhibitor of Cdc42 Rho family GTPase
2161	NSC 23766
	Selective inhibitor of Rac1-GEF interaction; antioncogenic
4225	OctMAB
	Dynamin inhibitor
2222	Rac1 Inhibitor F56, control peptide
	Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221)
2221	Rac1 Inhibitor W56
	Selective inhibitor of Rac1-GEF interaction
2849	SecinH3
	Sec7-specific GEF inhibitor (cytohesins)
Activators
Cat.No.	Product Name / Activity
1645	8CPT-2Me-cAMP, sodium salt
	Selective Epac activator
4853	8-pCPT-2-O-Me-cAMP-AM
	Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)