More Information »GTPases are a group of enzymes that catalyze hydrolysis of the γ phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP). Mg2+ ions are essential for catalytic activity. GTPases, often coupled to G proteins, are essential in signal transduction.

GTPase Products

Product Name / Activity
4793 CE3F4
Uncompetitive Epac1 inhibitor
1774 Dynamin inhibitory peptide
Dynamin inhibitor
1775 Dynamin inhibitory peptide, myristoylated
Cell-permeable dynamin inhibitor
1776 Dynamin inhibitory peptide, myristoylated (control)
Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)
2897 Dynasore
Non-competitive dynamin inhibitor
4222 Dynole 34-2
Dynamin I inhibitor
3872 EHT 1864
Potent inhibitor of Rac family GTPases
4773 ESI 09
EPAC inhibitor
3584 Golgicide A
Potent, specific and reversible inhibitor of GBF1 ArfGEF
4844 HJC 0350
Selective Epac2 inhibitor
5364 Hydroxy Dynasore
Dynamin inhibitor; analog of dynasore (Cat. No. 2897)
3792 ITX 3
Selective inhibitor of TrioN RhoGEF activity
3982 Mdivi 1
Dynamin inhibitor; attenuates mitochondrial division and apoptosis
4224 MitMAB
Dynamin inhibitor
4266 ML 141
Selective inhibitor of Cdc42 Rho family GTPase
2161 NSC 23766
Selective inhibitor of Rac1-GEF interaction; antioncogenic
4225 OctMAB
Dynamin inhibitor
2222 Rac1 Inhibitor F56, control peptide
Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221)
2221 Rac1 Inhibitor W56
Selective inhibitor of Rac1-GEF interaction
5411 RBC8
RalA and RalB GTPase inhibitor
5003 Rhosin hydrochloride
Rho GTPase inhibitor
4989 Salirasib
Ras inhibitor; also induces autophagy
2849 SecinH3
Sec7-specific GEF inhibitor (cytohesins)
4794 ZCL 278
Cdc42 inhibitor
Product Name / Activity
1645 8-CPT-2Me-cAMP, sodium salt
Selective Epac activator
4853 8-pCPT-2-O-Me-cAMP-AM
Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)
Product Name / Activity
5424 Deltarasin
High affinity PDEδ-KRAS interaction inhibitor
5475 Kobe 0065
H-Ras-cRaf1 interaction inhibitor; inhibits Raf signaling
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