R&D Systems Inc. Tocris Bioscience Boston Biochem

GTPase

More Information »GTPases are a group of enzymes that catalyze hydrolysis of the γ phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP). Mg2+ ions are essential for catalytic activity. GTPases, often coupled to G proteins, are essential in signal transduction.

GTPase Products

Inhibitors
Cat.No.
Product Name / Activity
1774 Dynamin inhibitory peptide
Dynamin inhibitor
1775 Dynamin inhibitory peptide, myristoylated
Cell-permeable dynamin inhibitor
1776 Dynamin inhibitory peptide, myristoylated (control)
Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)
2897 Dynasore
Non-competitive dynamin inhibitor
4222 Dynole 34-2
Dynamin I inhibitor
3872 EHT 1864
Potent inhibitor of Rac family GTPases
3584 Golgicide A
Potent, specific and reversible inhibitor of GBF1 ArfGEF
4844 HJC 0350
Selective Epac2 inhibitor
3792 ITX 3
Selective inhibitor of TrioN RhoGEF activity
3982 Mdivi 1
Dynamin inhibitor; attenuates mitochondrial division and apoptosis
4224 MitMAB
Dynamin inhibitor
4266 ML 141
Selective inhibitor of Cdc42 Rho family GTPase
2161 NSC 23766
Selective inhibitor of Rac1-GEF interaction; antioncogenic
4225 OctMAB
Dynamin inhibitor
2222 Rac1 Inhibitor F56, control peptide
Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221)
2221 Rac1 Inhibitor W56
Selective inhibitor of Rac1-GEF interaction
4989 Salirasib
Ras inhibitor; also induces autophagy
2849 SecinH3
Sec7-specific GEF inhibitor (cytohesins)
4794 ZCL 278
Cdc42 inhibitor
Activators
Cat.No.
Product Name / Activity
1645 8-CPT-2Me-cAMP, sodium salt
Selective Epac activator
4853 8-pCPT-2-O-Me-cAMP-AM
Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)
Related Categories

Quick Order

Find multiple products by catalog number

divider line

New Product E-alerts

Sign up for email updates from Tocris

e-alerts

Enter your email address below to sign up to receive our email updates:

divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.