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Cyclooxygenase
More Information »Cyclooxygenase (also known as COX, Prostaglandin-endoperoxide synthase, Prostaglandin G/H synthase) is expressed in cells in three isoforms. COX-1 (constitutive) and COX-2 (inducible) isoforms catalyze the rate-limiting step of prostaglandin production.
Cyclooxygenase Products
Inhibitors |
|
Cat.No. |
Product Name / Activity |
| 1706 | Acetaminophen |
| Cyclooxygenase inhibitor; may be selective for COX-3 | |
| 4092 | Aspirin |
| Cyclooxygenase inhibitor; NSAID | |
| 3786 | Celecoxib |
| Selective cyclooxygenase-2 (COX-2) inhibitor | |
| 4454 | Diclofenac sodium salt |
| Cyclooxygenase inhibitor; NSAID | |
| 1430 | DuP 697 |
| Cyclooxygenase-2 (COX-2) inhibitor | |
| 3871 | Etodolac |
| Selective cyclooxygenase-2 (COX-2) inhibitor; NSAID | |
| 2776 | FK 3311 |
| Cyclooxygenase-2 (COX-2) inhibitor | |
| 4522 | Flufenamic acid |
| Cyclooxygenase inhibitor; NSAID. Also activates TRPC6 | |
| 1769 | Flurbiprofen |
| Cyclooxygenase inhibitor | |
| 1507 | FR 122047 hydrochloride |
| Cyclooxygenase (COX-1) inhibitor | |
| 2796 | (S)-(+)-Ibuprofen |
| Cyclooxygenase inhibitor (COX-1 > COX-2) | |
| 1708 | Indomethacin |
| Cyclooxygenase inhibitor (COX-1 > COX-2) | |
| 2655 | Naproxen sodium |
| Cyclooxygenase inhibitor | |
| 4531 | NCX 4040 |
| NO-donating aspirin; anti-inflammatory and antitumor | |
| 4537 |
NCX 466
|
| Cyclooxygenase-inhibiting nitric oxide donor | |
| 3333 | NDT 9513727 |
| Cyclooxygenase inhibiting nitric oxide donor | |
| 4112 | Niflumic acid |
| Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist | |
| 2470 | Nimesulide |
| Cyclooxygenase-2 (COX-2) inhibitor | |
| 0942 | NS 398 |
| Cyclooxygenase-2 (COX-2) inhibitor | |
| 0960 | Piroxicam |
| Cyclooxygenase-1 (COX-1) inhibitor | |
| 1418 | Resveratrol |
| Cyclooxygenase inhibitor | |
| 1550 | SC 560 |
| Cyclooxygenase (COX-1) inhibitor | |
| 2895 | SC 58125 |
| Selective cyclooxygenase-2 (COX-2) inhibitor | |
| 3919 | SC 236 |
| Selective cyclooxygenase-2 (COX-2) inhibitor | |
| 1707 | Sulindac |
| Cyclooxygenase inhibitor (following metabolism to sulindac sulfide) | |
| 2510 | Talniflumate |
| Cyclooxygenase inhibitor. Also chloride channel blocker | |
| 2580 | Tenidap |
| NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3 | |
| 4206 | Valdecoxib |
| Selective and potent COX-2 inhibitor | |
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