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Bradykinin Receptors
Supporting information
Bradykinin and related kinins are a family of small peptides which act as mediators of pain and inflammation. They exert a variety of biological effects on the endothelium and peripheral circulation through their action on two G-protein-coupled bradykinin receptor subtypes, the B1 receptor and the B2 receptor. Bradykinin is an important pro-inflammatory molecule that causes vasodilation, plasma protein extravasation, smooth muscle contraction and pain.
To view external sources of pharmacological information for Bradykinin Receptors, please click here: IUPHAR Receptor Code and BJP Guide
View all products for Bradykinin Receptors »| Gene | Species | Gene Symbol | Gene Accession No. | Protein Accession No. |
|---|
| B1 | Human | BDKRB1 | NM_000710 | P46663 |
| Mouse | Bdkrb1 | NM_007539 | Q61125 | |
| Rat | Bdkrb1 | NM_030851 | P97583 | |
| B2 | Human | BDKRB2 | NM_000623 | P30411 |
| Mouse | Bdkrb2 | NM_009747 | P32299 | |
| Rat | Bdkrb2 | NM_173100 | P25023 |
Literature for Bradykinin Receptors
Peptide Hormone Receptors Product Listing
A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:
- Anterior Pituitary Regulation
- Blood Pressure Regulation
- Feeding and Appetite Regulation
- Glucose Regulation
- Peptide Hormone Processing
Pain Research Guide
A collection of over 250 products for pain research, the guide includes research tools for the study of:
- Nociception
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Cardiovascular Poster
Written by Janet Maguire and Anthony Davenport, this poster summarizes different GPCR classes of the vascular system and their cognate ligands. The predominant vasoactive response of blood vessels to specific receptor activation is also described. Endogenous ligands and Tocris compounds are listed.
Request copy | View all posters7-TM Receptor Signaling Poster
Written by Terry Kenakin et al, this poster highlights the multiple behaviors of seven-transmembrane (7-TM) receptors, including G-protein-dependent and -independent signaling and the concept of collateral efficacy. Compounds available from Tocris are listed.
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Peptide Hormone Receptors Product Listing
Highlights over 200 products for peptide hormone receptors. Reserve your free copy today and be amongst the first to receive it.
Pain Research Guide
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Highlights over 280 products for Pain research. Reserve copy
Regulation of Vascular Reactivity by GPCRs
Written by J.J. Maguire and A.P. Davenport
'Regulation of Vascular Reactivity by G-protein-coupled Receptors' summarizes the key GPCRs regulating vascular reactivity.
7-TM Receptor Signaling
Written by T. Kenakin et al
'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy
Tocris Events
Win a Kindle
British Cardiovascular Society Annual Conference 2013
June 3 - 5, 2013
London, UK
Booth Number: C54