Cyclin-Dependent Protein Kinases

More Information »Cdks (cyclin-dependent kinases) are heteromeric serine/threonine kinases that control progression through the cell cycle in concert with their regulatory subunits, the cyclins. Although there are 12 different cdk genes, only 5 have been shown to directly drive the cell cycle.

Cyclin-Dependent Protein Kinase Products

Product Name / Activity
2072 Aminopurvalanol A
Cyclin-dependent kinase inhibitor
2457 Arcyriaflavin A
Potent cdk4/cyclin D1 and CaM Kinase II inhibitor. Antiviral agent (anti-HCMV)
3968 AZD 5438
Potent cyclin-dependent kinase (cdk) 1, 2 and 9 inhibitor
5608 BS 181 dihydrochloride
Selective cdk7 inhibitor
3605 (R)-CR8
Dual cdk1/cdk5 inhibitor; also inhibits CK1
3610 (R)-DRF053 dihydrochloride
Dual cdk1/cdk5 inhibitor. Also inhibits CK1
3094 Flavopiridol hydrochloride
Cyclin-dependent kinase inhibitor
1532 10Z-Hymenialdisine
Pan kinase inhibitor; potently inhibits Cdk1, Cdk2, Cdk3 and Cdk5
1813 Indirubin-3'-oxime
Cyclin-dependent kinase inhibitor. Also inhibits other protein kinases
1398 Kenpaullone
Potent cyclin-dependent kinase inhibitor. Also inhibits GSK-3
2152 NSC 625987
Cyclin-dependent kinase 4 (cdk4) inhibitor
1867 NSC 663284
Cdc25 phosphatase inhibitor; blocks cdk1 and cdk2 activation
1937 NSC 693868
Cdk inhibitor. Also inhibits GSK-3
3135 NU 2058
Cdk1 and cdk2 inhibitor
3301 NU 6140
Cyclin-dependent kinase 2 (cdk2) inhibitor
1284 Olomoucine
Cyclin-dependent kinase inhibitor
1902 [Ala92]-p16 (84-103)
Cyclin-dependent kinase inhibitor
4786 PD 0332991 isethionate
Potent, selective Cdk4/6 inhibitor; brain penetrant
3140 PHA 767491 hydrochloride
Dual cdc7/cdk9 inhibitor. Also inhibits MK2
1580 Purvalanol A
Cyclin-dependent kinase inhibitor
1581 Purvalanol B
Cyclin-dependent kinase inhibitor
4181 Ro 3306
Cyclin-dependent kinase (cdk) 1 inhibitor
2609 Ryuvidine
Cyclin-dependent kinase 4 (CDK4) inhibitor; also SETD8 inhibitor
4875 Senexin A
Cyclin-dependent kinase 8 (cdk8) inhibitor
4075 SNS 032
Potent cdk2, cdk7 and cdk9 inhibitor
2907 SU 9516
Potent cdk2 inhibitor
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