Purinergic (P2X) Receptors

More Information »P2X receptors are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains.

Purinergic (P2X) Receptor Products

Product Name / Activity
3245 ATP disodium salt
P2 purinergic agonist
4080 ATPγS tetralithium salt
P2 agonist; ATP (Cat. No. 3245) analog
3312 BzATP triethylammonium salt
P2X7 agonist. Also P2X1 and P2Y1 partial agonist
3209 α,β-Methyleneadenosine 5'-triphosphate trisodium salt
P2-purinoceptor agonist
1062 2-Methylthioadenosine triphosphate tetrasodium salt
P2 purinergic agonist
Product Name / Activity
2972 A 438079 hydrochloride
Competitive P2X7 antagonist
3701 A 740003
Potent and selective P2X7 antagonist
4473 A 804598
Potent and selective P2X7 antagonist
4232 A 839977
Potent P2X7 antagonist
3323 AZ 10606120 dihydrochloride
Potent P2X7 receptor antagonist
3317 AZ 11645373
Potent and selective human P2X7 antagonist
3579 5-BDBD
Potent P2X4 receptor antagonist
5545 BX 430
Selective P2X4 allosteric antagonist
0845 Evans Blue tetrasodium salt
Selective P2X purinergic antagonist
5299 JNJ 47965567
Potent and selective P2X7 antagonist; brain penetrant
1277 KN-62
Non-competitive P2X7 antagonist
1240 NF 023
Selective, competitive P2X1 antagonist
2548 NF 110
Potent P2X3 antagonist
2450 NF 157
Selective P2Y11/P2X1 antagonist
1199 NF 279
Potent and selective P2X1 antagonist
1391 NF 449
Highly selective P2X1 antagonist
0625 PPADS tetrasodium salt
P2 purinergic antagonist
0683 iso-PPADS tetrasodium salt
P2X antagonist
1309 PPNDS
Potent, selective P2X1 antagonist
2188 Ro 0437626
Selective P2X1 antagonist
4391 Ro 51
Potent P2X3, P2X2/3 antagonist
3052 RO-3
Selective P2X3 and P2X2/3 antagonist
1472 Suramin hexasodium salt
Non-selective P2 antagonist
4386 TC-P 262
Selective P2X3, P2X2/3 antagonist
2464 TNP-ATP triethylammonium salt
Potent, selective P2X antagonist
Product Name / Activity
3385 GW 791343 hydrochloride
P2X7 allosteric modulator
1260 Ivermectin
Positive allosteric modulator for P2X4 receptor
4922 Purotoxin 1
Potent P2X3 modulator
Product Name / Activity
5157 DMNPE-caged ATP diammonium salt
Caged ATP
5156 Ivermectin B1a-d2
Deuterated ivermectin B1a (Cat. No. 1260)
1203 MRS 2219
Potentiates P2X1-mediated responses
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