Chloride Channels

More Information »Chloride channels are a family of anion-selective channels involved in the regulation of the excitability of neurons, skeletal, cardiac and smooth muscle, cell volume regulation, transepithelial salt transport and the acidification of intra- and extracellular compartments.

Chloride Channel Products

Activators
Cat.No.	Product Name / Activity
1422	DCEBIO
	Activates Cl^- conductance and hK_Ca3.1 channels
4876	Eact
	Activator of Ca²⁺-activated Cl^- channel transmembrane protein 16A (TMEM16A)
Blockers
Cat.No.	Product Name / Activity
4877	CaCCinh-A01
	Calcium-activated chloride channel (CaCC) inhibitor
3430	CFTR_inh 172
	Voltage-independent, selective CFTR chloride channel blocker
1412	Chromanol 293B
	Blocks I_CFTR. Also I_Ks blocker
1540	DCPIB
	Selective blocker of VSAC/I_{Cl, swell}. Inhibits glucose-stimulated insulin release
4523	DIDS
	Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor
0911	Glibenclamide
	Blocks CFTR Cl^- channels. Also K_ATP channel blocker
1646	Lonidamine
	CFTR Cl^- channel blocker. Also anticancer agent
0593	NPPB
	Chloride channel blocker
4538	T16Ainh - A01
	Ca²⁺-activated Cl^- channel transmembrane protein 16A (TMEM16A) inhibitor
2510	Talniflumate
	CaCC blocker and Cl^-/HCO₃^- exchange)
Other
Cat.No.	Product Name / Activity
0963	9-AC
	Chloride transport inhibitor
3143	KM 11060
	Corrects F508del-CFTR trafficking
3943	PG 01
	CFTR mutants potentiator