Voltage-gated Potassium (KV) Channels

More Information »Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The α-subunits contain a single pore-forming region and combine to form tetramers.

Voltage-gated Potassium (KV) Channel Products

Product Name / Activity
4949 MaxiPost
Potassium channel modulator; exerts subtype-specific effects
Product Name / Activity
2867 Flupirtine maleate
KV7 channel activator
4305 ICA 069673
KV7.2/KV7.3 channel opener
4950 ICA 110381
KV7.2/7.3 activator; displays anticonvulsant properties
2660 L-364,373
KV7.1 channel activator, activates IKs
4519 ML 213
KV7.2 and KV7.4 channel opener
4777 ML 277
Selective Kv7.1 (KCNQ1) potassium channel activator; augments IKs current
3062 NS 1643
KV11.1 (hERG) channel activator; antiarrhythmic
4462 NS 3623
KV11.1 (hERG) channel activator; antiarrhythmic
4166 NS 5806
KV4.3 channel activator
2830 PD 118057
Selective KV11.1 (hERG) channel activator
Product Name / Activity
4812 ADWX 1
Potent and selective KV1.3 channel blocker
5195 Agitoxin 2
Potent Shaker K+ channel blocker
0876 AM 92016 hydrochloride
KV channel blocker
0940 4-Aminopyridine
Non-selective KV channel blocker
5659 AmmTX3
KV4 channel blocker
3489 Astemizole
Potent KV11.1 (hERG) channel blocker. Also histamine H1 antagonist
hKV11.1 (hERG), hKV1.3 and hKV1.5 channel blocker. Also Ca2+ chelator
5184 BDS I
Potent and reversible Kv3.4 potassium channel blocker; neuroprotective
1412 Chromanol 293B
IKs blocker. Also blocks ICFTR
1475 (-)-[3R,4S]-Chromanol 293B
IKs blocker. Enantiomer of Chromanol 293B (Cat. No. 1412)
1399 CP 339818 hydrochloride
Non-peptide, potent KV1.3 channel blocker
3757 Dofetilide
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
2533 DPO-1
Blocker of KV1.5 channel and IKur current
1808 E-4031 dihydrochloride
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
5011 HMR 1556
Potent and selective Iks channel blocker
3899 JNJ 303
Potent and selective IKs blocker
3564 Kaliotoxin
KV and KCa blocker
4130 KN 92
K+ channel (Kv) blocker. Inactive analog of KN 93
1278 KN 93
K+ channel blocker (KV); also inhibitor of CaM Kinase II
1999 Linopirdine dihydrochloride
KV7 (KCNQ) channel blocker
3563 Margatoxin
Potent KV1.3 channel blocker
4665 ProTx I
CaV3.1 channel blocker; also inhibits NaV1.8 and KV2.1
4367 Psora 4
Potent KV1.3 channel blocker
3557 RuBi-4AP
Caged 4-aminopyridine; a non-selective KV channel blocker
3220 ShK-Dap22
Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro
3948 Terfenadine
KV11.1 (hERG) and Kir6 (KATP) channel blocker. Also H1 antagonist
3068 Tetraethylammonium chloride
Non-selective K+ channel blocker
3829 UK 78282 hydrochloride
Blocker of KV1.3 and KV1.4 channels
2000 XE 991 dihydrochloride
Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents
Product Name / Activity
2007 Fluticasone propionate
Selective glucocorticoid agonist; KV1 potentiator
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