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Voltage-gated Potassium (K_V) Channels

More Information »Voltage-gated potassium channels (K_V) belong to the 6-TM family of potassium channel that also comprises the Ca²⁺-activated Slo (actually 7-TM) and the Ca²⁺-activated SK subfamilies. The α-subunits contain a single pore-forming region and combine to form tetramers.

Voltage-gated Potassium (K_V) Channel Products

Activators
Cat.No.	Product Name / Activity
2867	Flupirtine maleate
	KV7 channel activator
4305	ICA 069673
	KV7.2/KV7.3 channel opener
2660	L-364,373
	KV7.1 channel activator, activates IKs
4519	ML 213
	KV7.2 and KV7.4 channel opener
3062	NS 1643
	KV11.1 (hERG) channel activator. Antiarrhythmic
4462	NS 3623
	KV11.1 (hERG) channel activator. Antiarrhythmic
4166	NS 5806
	KV4.3 channel activator
2830	PD 118057
	Selective KV11.1 (hERG) channel activator
Blockers
Cat.No.	Product Name / Activity
4812	ADWX 1
	Potent and selective KV1.3 channel blocker
0876	AM 92016 hydrochloride
	KV channel blocker
0940	4-Aminopyridine
	Non-selective KV channel blocker
3489	Astemizole
	Potent KV11.1 (hERG) channel blocker. Also histamine H1 antagonist
2787	BAPTA AM
	hKV11.1 (hERG), hKV1.3 and hKV1.5 channel blocker. Also Ca2+ chelator
1412	Chromanol 293B
	IKs blocker. Also blocks ICFTR
1475	(-)-[3R,4S]-Chromanol 293B
	IKs blocker. Enantiomer of Chromanol 293B (Cat. No. 1412)
1399	CP 339818 hydrochloride
	Non-peptide, potent KV1.3 channel blocker
3757	Dofetilide
	KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
2533	DPO-1
	Blocker of KV1.5 channel and IKur current
1808	E-4031 dihydrochloride
	KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
3899	JNJ 303
	Potent and selective IKs blocker
3564	Kaliotoxin
	KV and KCa blocker
1278	KN-93
	K+ channel blocker (KV). Also inhibitor of CaM Kinase II
1999	Linopirdine dihydrochloride
	KV7 (KCNQ) channel blocker
3563	Margatoxin
	Potent KV1.3 channel blocker
4665	ProTx I
	CaV3.1 channel blocker; also inhibits NaV1.8 and KV2.1
4367	Psora 4
	Potent KV1.3 channel blocker
3557	RuBi-4AP
	Caged 4-aminopyridine; a non-selective KV channel blocker
3948	Terfenadine
	KV11.1 (hERG) and Kir6 (KATP) channel blocker. Also H1 antagonist
3829	UK 78282 hydrochloride
	Blocker of KV1.3 and KV1.4 channels
2000	XE 991 dihydrochloride
	Potent, selective KCNQ channel blocker; blocks M-current
Other
Cat.No.	Product Name / Activity
2007	Fluticasone propionate
	Selective glucocorticoid agonist; KV1 potentiator

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