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STIM-Orai Channels

More Information »STIM-Orai channels have recently been identified as the underlying molecular mechanism of store-operated calcium entry (SOCE). STIM (stromal interaction molecule) proteins are ER Ca²⁺ sensors. Orai proteins are STIM binding partners that form the channel pore.

STIM-Orai Channel Products

Inhibitors
Cat.No.	Product Name / Activity
0431	ML 9 hydrochloride
	STIM1-plasma membrane interaction inhibitor. Also MLCK inhibitor
1147	SKF 96365 hydrochloride
	STIM1-mediated Ca2+ influx inhibitor
3939	YM 58483
	Inhibits CRAC channels
Other
Cat.No.	Product Name / Activity
1224	2-APB
	Increases STIM-Orai channel conductivity and reduces selectivity

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