Vasopressin Receptors

More Information »Vasopressin receptors are a group of G-protein-coupled receptors that mediate vasoconstriction, antidiuresis and ACTH release. They are currently divided into three subtypes, V_1A, V_1B and V₂ and are closely related to oxytocin receptors (OT).

Vasopressin Receptor Products

Agonists
Cat.No.	Product Name / Activity
3126	d[Cha⁴]-AVP
	Potent and selective human V_1B agonist
3396	Desmopressin
	Synthetic vasopressin analog; V_1B and V₂ agonist
2935	[Arg⁸]-Vasopressin
	Antidiuretic hormone
2934	[Lys⁸]-Vasopressin
	Antidiuretic hormone
3127	d[Leu⁴,Lys⁸]-VP
	Selective V_1B agonist
Antagonists
Cat.No.	Product Name / Activity
3377	(d(CH₂)₅¹,Tyr(Me)²,Arg⁸)-Vasopressin
	Selective vasopressin V_1A antagonist
3924	OPC 21268
	Orally active vasopressin V₁ antagonist
2310	SR 49059
	Selective, orally active vasopressin V_1A receptor antagonist

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7-TM Receptor Signaling

Written by T. Kenakin et al

'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy