R&D Systems Inc. Tocris Bioscience Boston Biochem

ATM and ATR Kinases

More Information »ATM (Ataxia telangiectasia mutated) and ATR (Ataxia telangiectasia and Rad3 related) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases which are part of the phosphatidylinositol 3' kinase-like kinase (PIKK) enzyme family.

ATM and ATR Kinase Products

Inhibitors
Cat.No.
Product Name / Activity
3544 KU 55933
Potent and selective ATM kinase inhibitor
4176 KU 60019
Potent ATM kinase inhibitor
3190 Mirin
MRN-ATM pathway inhibitor
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Cancer Research Guide

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Kinases Product Listing

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Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Some of the most potent
kinase inhibitors all on one plate

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

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Checkpoint Kinases & the DNA Damage Response

Written by Michelle D. Garrett and Ian Collins

Cell Cycle Kinases Poster

A summary of the response of the checkpoint kinase signaling network to DNA damage, including activation of DNA repair, cell-cycle arrest, senescence and apoptosis.

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New Product Guide

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Highlights over 130 new products added in the second half of 2013. Request a copy or view PDF today.

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Tocris Events

Immunology 2014

Immunology 2014

May 2-6, 2014

Pittsburgh, Pennsylvania

Booth Number: 523