TGF-β Receptors

More Information »The transforming growth factor-β family of polypeptides (TGF-β1-3) are involved in the regulation of cellular processes, including division, differentiation, motility, adhesion and death. TGF-β signals by binding the type II receptor (TGF-βRII) which activates the type I receptor (TGF-βRI).

TGF-β Receptor Products

Inhibitors
Cat.No.	Product Name / Activity
2939	A 83-01
	Selective inhibitor of TGF-βRI, ALK4 and ALK7
2902	D 4476
	TGF-βRI inhibitor. Also inhibits CK1
3264	GW 788388
	Selective inhibitor of TGF-βRI
2718	LY 364947
	Selective inhibitor of TGF-βRI
3742	RepSox
	Selective inhibitor of TGF-βRI
1614	SB 431542
	Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
3263	SB 505124
	Selective inhibitor of TGF-βRI, ALK4 and ALK7
3211	SB 525334
	Selective inhibitor of TGF-βRI
3269	SD 208
	Potent ATP-competitive TGF-βRI inhibitor

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TGF-β signaling is involved in the regulation of growth and proliferation of cells along with migration, differentiation and apoptosis. View pathway or download PDF today.