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Insulin and Insulin-like Receptors
More Information »Insulin receptors (IRs) and insulin-like growth factor receptors (IGFRs) are formed from two subunits, each of which is comprised of an extracellular α-subunit and a transmembrane β-subunit with intracellular tyrosine kinase activity. IR homodimers are activated by insulin.
Insulin and Insulin-like Receptor Products
Inhibitors |
|
Cat.No. |
Product Name / Activity |
| 4774 |
BMS 536924
|
| Dual IR/IGF1R inhibitor | |
| 2956 | Picropodophyllotoxin |
| Selective IGF1R inhibitor | |
| 2768 | PQ 401 |
| IGF1R inhibitor | |
Activators |
|
Cat.No. |
Product Name / Activity |
| 1819 | Demethylasterriquinone B1 |
| Selective insulin RTK activator | |
| 3435 |
Insulin (human) recombinant expressed in yeast |
| Endogenous peptide agonist | |
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Kinases Product Listing
Highlights over 350 products for kinase research. Request a copy or view PDF today.
Kinase Inhibitor Toolbox
80 Kinase inhibitors
pre-dissolved in DMSO
Some of the most potent
kinase inhibitors all on one plate
Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.
Appetite Modulation
Written by Sonia A. Tucci, Lynsay Kobelis & Tim Kirkham. Request a copy or view PDF today.
VEGF Pathway & Anti-Angiogenic Therapy
Written by N. Ferrara & Y. Crawford
A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.
Gut Hormones and the Regulation of Appetite
Written by V.J. Taylor et al
'Gut Hormones and the Regulation of Appetite' summarizes the neuropeptide modulators and gut hormones that influence appetite
Insulin Pathway
Signals through the insulin pathway are fundamental for the regulation of intracellular glucose levels. View pathway or download PDF today.
Tocris Events
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11th Annual Meeting of the International Society for Stem Cell Research
June 12 - 15, 2013
Boston, MA
Booth Number: 213