R&D Systems Inc. Tocris Bioscience Boston Biochem

Multidrug Transporters

More Information »ATP-binding cassette (ABC) transporters form one of the largest groups of paralogous protein families that have a wide diversity of functions and substrates. Specificity has been shown for small and large molecules, highly charged molecules and highly hydrophobic systems.

Multidrug Transporter Products

Modulators
Cat.No.
Product Name / Activity
2944 XR 9051 HCl
Potent modulator of P-gp-mediated MDR
Inhibitors
Cat.No.
Product Name / Activity
4193 CP 100356 hydrochloride
P-gp inhibitor
4646 Elacridar hydrochloride
P-gp inhibitor
3588 Estropipate
Estrogen receptor agonist and OATP1B1 inhibitor
2876 Fumitremorgin C
Inhibitor of BCRP-mediated multidrug resistance
3241 Ko 143
Potent and selective BCRP inhibitor
4169 KS 176
Selective BCRP inhibitor
2338 MK 571
MRP inhibitor. Also CysLT1 (LTD4) inverse agonist
4107 Probenecid
MRP inhibitor
4042 PSC 833
Inhibitor of P-gp-mediated MDR
3918 Pyrimethamine
Potent inhibitor of multi-drug and toxin extrusion (MATE) transporters; also inhibits DHFR
3722 Reversan
Selective MRP1 and P-gp inhibitor
Other
Cat.No.
Product Name / Activity
5119 Calcein AM
Substrate for MDR

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