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Multidrug Transporters

More Information »ATP-binding cassette (ABC) transporters form one of the largest groups of paralogous protein families that have a wide diversity of functions and substrates. Specificity has been shown for small and large molecules, highly charged molecules and highly hydrophobic systems.

Multidrug Transporter Products

Modulators
Cat.No.	Product Name / Activity
2944	XR 9051 HCl
	Potent modulator of P-gp-mediated MDR
Inhibitors
Cat.No.	Product Name / Activity
4193	CP 100356 hydrochloride
	P-gp inhibitor
4646	Elacridar hydrochloride
	P-gp inhibitor
3588	Estropipate
	Estrogen receptor agonist and OATP1B1 inhibitor
2876	Fumitremorgin C
	Inhibitor of BCRP-mediated multidrug resistance
3241	Ko 143
	Potent and selective BCRP inhibitor
2338	MK 571
	MRP inhibitor. Also CysLT1 (LTD4) inverse agonist
4107	Probenecid
	MRP inhibitor
4042	PSC 833
	Inhibitor of P-gp-mediated MDR
3918	Pyrimethamine
	Potent inhibitor of multi-drug and toxin extrusion (MATE) transporters; also inhibits DHFR
3722	Reversan
	Selective MRP1 and P-gp inhibitor

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