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Epithelial Sodium Channels
More Information »Epithelial sodium channels (ENaCs) are members of the ENaC/Deg (epithelial amiloride-sensitive Na+ channel and degenerin) family of ion channels. They are highly selective Na+ channels that are localized to polarized epithelial cells. ENaCs are responsible for sodium reabsorption in the distal kidney tubule, and transport Na+ across the epithelium. They have similar functions in alveoli and the colon.
Epithelial Sodium Channel Products
Antagonists |
|
Cat.No. |
Product Name / Activity |
| 3379 |
Phenamil
|
| Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels | |
Activators |
|
Cat.No. |
Product Name / Activity |
| 0464 | Capsazepine |
| Activator of ENaCδ. Also vanilloid receptor antagonist | |
Blockers |
|
Cat.No. |
Product Name / Activity |
| 3380 |
Benzamil
|
| NCX inhibitor, Deg/ENaC channel blocker; amiloride (Cat. No. 0890) derivative | |
