R&D Systems Inc. Tocris Bioscience Boston Biochem

Cytochrome P450

More Information »Cytochrome P450 (CYP450) enzymes are a diverse group of catalysts that contains 57 members in humans. CYPs are usually membrane-bound and are localized to the inner mitochondrial or endoplasmic reticular membrane. CYPs have oxygenase activity.

Cytochrome P450 Products

Inhibitors
Cat.No.
Product Name / Activity
5038 ABT
Cytochrome P450 inhibitor; inhibits 20-HETE synthesis
3388 Anastrozole
Potent aromatase (CYP19) inhibitor
4096 Clotrimazole
Cytochrome P450 inhibitor; antifungal
3759 Exemestane
Steroidal aromatase (CYP19) inhibitor
1103 Ketoconazole
Cytochrome P450c17 inhibitor
4382 Letrozole
Potent, reversible non-steroidal aromatase inhibitor
2705 Liarozole hydrochloride
Cytochrome P450 (CYP26) inhibitor; blocks retinoic acid metabolism
3292 Metyrapone
Cytochrome P450 inhibitor
2583 Omeprazole
CYP2C19, CYP2C9 and CYP3A inhibitor. Also H+,K+-ATPase inhibitor
4252 PF 4981517
Selective CYP3A4 inhibitor
1509 TMS
Cytochrome P450 1B1 inhibitor
3278 YM 511
Potent aromatase (CYP19) inhibitor
Substrates
Cat.No.
Product Name / Activity
4815 3-Cyano-7-ethoxycoumarin
Fluorescent cytochrome P450 substrate
3276 Mephenytoin
CYP2C19 substrate. Anticonvulsant
4814 Methoxyresorufin
Fluorometric CYP450 substrate
4816 Pentoxyresorufin
Fluorometric cytochrome P450 substrate
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