Hydroxycarboxylic Acid Receptors
More Information »Hydroxycarboxylic acid (HCA) receptors are Gi/Go protein-coupled receptors for which hydroxycarboxylic acids are endogenous ligands. Three HCA receptors are known to exist: HCA1 (GPR81), HCA2 (GPR109A) and HCA3 (GPR109B).
Hydroxycarboxylic Acid Receptor Products
Product Name / Activity
|Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors|
|Selective agonist for the GPR109B (HM74) receptor. Antilipolytic|
|HCA2 (GPR109A) partial agonist|
|Activator of Nrf2 pathway; GPR109A agonist|
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Potent, selective LRRK2 inhibitor
Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.