Chemokine Receptors

More Information »Chemokines (chemotactic cytokines) belong to a family of chemoattractant molecules involved in the directed migration of immune cells. Over fifty human chemokines have been identified that can be categorized into four groups; CC, CXC, CX3C and C (XCL1 and XCL2).

Chemokine Receptor Products

Product Name / Activity
4780 VUF 11207 fumarate
Potent CXCR7 agonist
2565 ZK 756326
Selective, non-peptide CCR8 agonist
Product Name / Activity
3299 AMD 3100 octahydrochloride
Highly selective CXCR4 antagonist
4179 AMD 3465 hexahydrobromide
Potent, selective CXCR4 antagonist
4487 (±)-AMG 487
CXCR3 antagonist; inhibits cell migration and metastasis
3129 BMS CCR2 22
High affinity, potent CCR2 antagonist
3496 BX 471
Potent, selective CCR1 antagonist
2769 BX 513 hydrochloride
Selective CCR1 antagonist
3581 C 021 dihydrochloride
Potent CCR4 antagonist
5130 CTCE 9908
CXCR4 antagonist; antitumor
2423 DAPTA
Chemokine receptor 5 (CCR5) antagonist
4320 FC 131
CXCR4 antagonist
4306 INCB 3284 dimesylate
Selective CCR2 antagonist
4596 IT1t dihydrochloride
Potent CXCR4 antagonist
2595 J 113863
Potent CCR1 chemokine receptor antagonist
5176 JNJ 27141491
Potent and selective human CCR2 antagonist
3756 Maraviroc
Selective CCR5 antagonist
4528 (±)-NBI 74330
Potent and selective CXCR3 antagonist
2089 RS 102895 hydrochloride
CCR2b chemokine receptor antagonist
2517 RS 504393
Highly selective CCR2 chemokine receptor antagonist
2725 SB 225002
Potent and selective CXCR2 antagonist
2724 SB 265610
Potent CXCR2 antagonist
4213 SB 297006
Potent and selective CCR3 antagonist
3650 SB 328437
Potent and selective CCR3 antagonist
4300 TC 14012
CXCR4 antagonist; CXCR7 agonist
3664 Teijin compound 1
Potent CCR2b antagonist
2757 UCB 35625
Potent CCR1 and CCR3 antagonist
3951 WZ 811
Potent CXCR4 antagonist
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