R&D Systems Inc. Tocris Bioscience Boston Biochem

Chemokine Receptors

More Information »Chemokines (chemotactic cytokines) belong to a family of chemoattractant molecules involved in the directed migration of immune cells. Over fifty human chemokines have been identified that can be categorized into four groups; CC, CXC, CX3C and C (XCL1 and XCL2).

Chemokine Receptor Products

Agonists
Cat.No.
Product Name / Activity
2565 ZK 756326
Selective, non-peptide CCR8 agonist
Antagonists
Cat.No.
Product Name / Activity
3299 AMD 3100 octahydrochloride
Highly selective CXCR4 antagonist
4179 AMD 3465 hexahydrobromide
Potent, selective CXCR4 antagonist
3129 BMS CCR2 22
High affinity, potent CCR2 antagonist
3496 BX 471
Potent, selective CCR1 antagonist
2769 BX 513 hydrochloride
Selective CCR1 antagonist
3581 C 021 dihydrochloride
Potent CCR4 antagonist
2423 DAPTA
Chemokine receptor 5 (CCR5) antagonist
4320 FC 131
CXCR4 antagonist
4306 INCB 3284 dimesylate
Selective CCR2 antagonist
4596 IT1t dihydrochloride
Potent CXCR4 antagonist
2595 J 113863
Potent CCR1 chemokine receptor antagonist
3756 Maraviroc
Selective CCR5 antagonist
2089 RS 102895 hydrochloride
CCR2b chemokine receptor antagonist
2517 RS 504393
Highly selective CCR2 chemokine receptor antagonist
2725 SB 225002
Potent and selective CXCR2 antagonist
2724 SB 265610
Potent CXCR2 antagonist
4213 SB 297006
Potent and selective CCR3 antagonist
3650 SB 328437
Potent and selective CCR3 antagonist
4300 TC 14012
CXCR4 antagonist; CXCR7 agonist
3664 Teijin compound 1
Potent CCR2b antagonist
2757 UCB 35625
Potent CCR1 and CCR3 antagonist
3951 WZ 811
Potent CXCR4 antagonist
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Immunology Research Guide

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New Therapies and Challenges in Asthma

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Asthma Poster

'New Therapies, Challenges, and Breakthroughs in Asthma' highlights key pathways and new therapies used to treat asthma, including those currently in clinical development.

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7-TM Poster

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Written by N. Ferrara & Y. Crawford

Angiogenesis Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

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NPG

Highlights over 130 new products added in 2012. Request a copy or view PDF today.

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