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Protein Kinase C
More Information »Protein kinase C (PKC) refers to a family of serine/threonine protein kinases grouped by their activation mechanism. Conventional PKCs (cPKC α-, βI- , βII- and γ-) are activated by phosphatidylserine in a calcium dependent manner and can bind diacylglycerol.
Protein Kinase C Products
Inhibitors |
|
Cat.No. |
Product Name / Activity |
| 4128 |
Bisindolylmaleimide II
|
| Potent PKC inhibitor and nicotinic receptor antagonist | |
| 0543 | C-1 |
| Protein kinase C inhibitor | |
| 1626 | Calphostin C |
| Potent, selective and photo-dependent PKC inhibitor | |
| 2442 | CGP 53353 |
| Selective inhibitor of PKCβII | |
| 1330 | Chelerythrine chloride |
| Cell-permeable protein kinase C inhibitor | |
| 0749 | Dihydrosphingosine |
| Protein kinase C inhibitor | |
| 0741 | GF 109203X |
| Protein kinase C inhibitor | |
| 2253 | Go 6976 |
| Potent protein kinase C inhibitor; selective for α and β isozymes | |
| 2285 | Go 6983 |
| Broad spectrum PKC inhibitor | |
| 2287 | K-252c |
| Protein kinase C inhibitor | |
| 4738 |
LY 333531 hydrochloride
|
| Protein kinase C inhibitor; selective for β isozymes | |
| 1900 | [Ala107]-MBP (104-118) |
| Protein kinase C inhibitor | |
| 1901 | [Ala113]-MBP (104-118) |
| Protein kinase C inhibitor | |
| 1193 | Melittin |
| Inhibits protein kinase C and cAMP-dependent protein kinase | |
| 0609 | (±)-Palmitoylcarnitine chloride |
| Protein kinase C inhibitor | |
| 4058 | PKC (19-36) |
| Pseudosubstrate peptide; inhibitor of PKC | |
| 4059 | [Glu27]-PKC (19-36) |
| Inactive control peptide for PKC (19-36) (Cat. No. 4058) | |
| 2992 | PKC 412 |
| Protein kinase C inhibitor | |
| 1792 | PKC β pseudosubstrate |
| Selective cell-permeable PKC inhibitor peptide (attached to vector) | |
| 1791 | PKC ζ pseudosubstrate |
| PKC ζ inhibitor peptide (attached to cell-permeable vector) | |
| 1587 | Ro 32-0432 hydrochloride |
| Potent, orally active PKC inhibitor | |
| 1610 | Rottlerin |
| Reported PKCδ inhibitor | |
| 0633 | D-erythro-Sphingosine (synthetic) |
| Protein kinase C inhibitor | |
| 4221 | TCS 21311 |
| PKCα and PKCθ inhibitor. Also inhibits JAK3 | |
| 2549 | ZIP |
| Cell-permeable inhibitor of atypical PKC isozyme PKMζ | |
| 3215 | ZIP (Scrambled) |
| Control peptide for ZIP (Cat. No. 2549) | |
| 3290 | ZIP, Biotinylated |
| Biotinylated peptide for ZIP (Cat. No. 2549) | |
Activators |
|
Cat.No. |
Product Name / Activity |
| 2383 | Bryostatin 1 |
| Protein kinase C activator | |
| 3091 | FR 236924 |
| Selective PKCε activator | |
| 3651 | (-)-Indolactam V |
| Protein kinase C activator | |
| 4054 |
PEP 005
|
| Protein kinase C activator | |
| 4153 | Phorbol 12,13-dibutyrate |
| Protein kinase C activator | |
| 1201 | Phorbol 12-myristate 13-acetate |
| Protein kinase C activator | |
| 1887 | PKC fragment (530-558) |
| Potent activator of protein kinase C | |
| 1790 | Pseudo RACK1 |
| Protein kinase C activator peptide (attached to cell permeable vector) | |
| 0430 | SC-10 |
| Protein kinase C activator | |
| 0433 | SC-9 |
| Protein kinase C activator | |
Other |
|
Cat.No. |
Product Name / Activity |
| 3427 | Oncrasin 1 |
| Induces abnormal nuclear aggregation of PKCι; proapoptotic | |
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