R&D Systems Inc. Tocris Bioscience Boston Biochem

Microtubules

More Information »Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of α- and β-tubulin polymers. Each microtubule is polarized; at one end α-subunits are exposed (-) and at the other, β-subunits are exposed (+).

Microtubules Products

Inhibitors
Cat.No.
Product Name / Activity
5075 Harmine
Potent and selective Dyrk1A inhibitor; inhibits tau phosphorylation
4997 INDY
Dyrk1A/B inhibitor; inhibits abberant tau phosphorylation
Other
Cat.No.
Product Name / Activity
4138 ABT 751
Inhibitor of microtubule polymerization; antimitotic and antitumor
1364 Colchicine
Inhibitor of tubulin
1495 Combretastatin A4
Inhibits tubulin polymerization. Antitumor, antiangiogenic and antimetastatic
1643 D-64131
Inhibitor of tubulin polymerization. Antitumor in vivo
4056 Docetaxel
Microtubule stabilizer
3502 Epothilone B
Microtubule stabilization agent; promotes tubulin polymerization
2226 Flutax 1
Fluorescent taxol derivative
3728 Indibulin
Microtubule destabilizer
3213 Methylene Blue
Inhibitor of tau aggregation
1228 Nocodazole
Microtubule inhibitor
1697 Noscapine hydrochloride
Tubulin inhibitor; induces apoptosis
1097 Taxol
Promotes assembly and inhibits disassembly of microtubules
4286 UA 62784
Inhibits microtubule polymerization
1256 Vinblastine sulfate
Disrupts microtubules
1257 Vincristine sulfate
Disrupts microtubules
3401 Vinorelbine ditartrate
Selective mitotic microtubule antagonist
3101 XRP44X
Microtubule depolymerization agent. Also Ras-Net pathway inhibitor
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