Pharmacology
All Targets
7-TM Receptors
Ion Channels
Nuclear Receptors
Enzyme-Linked Receptors
Transporters
Enzymes
Other Pharmacology
Cellular Processes
Angiogenesis
Apoptosis
Cell Cycle
Cell Metabolism
Cytoskeleton & Motor Proteins
ECM & Adhesion Molecules
Epigenetics 
Signal Transduction
Stem Cells
Signaling Pathways
Product Type
All Products
New Products
Small Molecules
Peptides
Controlled Substances
Toxins
Caged Compounds
Fluorescent Probes
Screening Libraries
Ligand Sets
Other Product Types
Research Area
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
Signal Transduction
Stem Cells
Signaling Pathways
Product Type
All Products
New Products
Small Molecules
Peptides
Controlled Substances
Toxins
Caged Compounds
Fluorescent Probes
Screening Libraries
Ligand Sets
Other Product Types
Research Area
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
Home » Signaling Pathways » TLR Signaling Pathway
TLR4
TLR5
TLR2/6
TLR1/2
Apoptosis
PI3K
JNK
ERK
p38
MAPK IKK IκB AP-1 AP-1 NF-κB NF-κB Rac1 MEK1/2 Caspase-8 Akt Immune Response Inflammation Cytokines
MAPK IKK IκB AP-1 AP-1 NF-κB NF-κB Rac1 MEK1/2 Caspase-8 Akt Immune Response Inflammation Cytokines
The toll-like receptors (TLRs) act in response to molecular patterns found in microbes such as bacteria and viruses that pose a biological threat. The signaling pathway leads to the activation of innate and acquired immunity along with an inflammatory response and the upregulation of cytokines.
Questions? Comments? Leave feedback.
