Neurochemicals | Signal Transduction Agents | Peptides | Biochemicals
Tocris Bioscience : www.tocris.com
Tocris Bioscience : www.tocris.com High Performance Life Science Reagents
New Products for November 2007
Cytochrome P450 inhibitor
Liarozole
Inhibits several cytochrome P450 enzymes including aromatase (CYP19) and retinoic acid 4-hydroxylase (CYP26). Blocks retinoic acid metabolism (retinoic acid metabolism blocking agent, RAMBA).
Related Products: TMS Ketoconazole Retinoic Acid Related Products
Selective GnRH receptor antagonist
AG 045572
Suppresses testosterone and luteinising hormone (LH) levels in vivo.
GnRH Related Products: Nafarelin T 98475
Histone deacetylase inhibitor
M 344
Induces terminal cell differentiation and causes an increase in hyperacetylated histone H4.
HDAC Related Products: NSC 3852 Valproic acid 4-Phenylbutyrate
Mixed 5-HT2A/D2 antagonist
Risperidone
Atypical antipsychotic agent that displays mixed 5-HT2A/D2 receptor antagonism (Ki values are 0.4 and 3.13 nM respectively).
Related Products: Amperozide Melperone Clozapine
Selective Inhibitor of PTP1B
TCS 401
Displays > 200-fold selectivity over CD45 D1D2, PTPβ, PTPε D1, SHP-1, PTPα D1 and LAR D1D2.
Phosphatase Related Products: BVT 948 Sodium Orthovanadate Tautomycetin
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