New Products for September 2007

Potent and selective sst ₅ agonist
L-817,818
Displays > 8-fold selectivity over other sst receptors. Inhibits growth hormone release from rat pituitary cells (EC₅₀ = 3.1 nM).
sst Related Products: Seglitide Octreotide NNC 26-9100

Antagonist of neurosteroid potentiation of GABA_A
17-PA
Selective antagonist of neurosteroid potentiation and direct gating of GABA_A receptors.
GABA Related Products: Ganaxolone (-)-Bicuculline methiodide Tracazolate

Selective A_2B antagonist
MRS 1754
K_i values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA_2B, rA₁, hA₁, hA_2A, hA₃ and rA_2A receptors respectively.
A_2B Related Products: PSB 1115 MRS 1706 CV 1808

GABA uptake inhibitor
NNC 05-2090
Displays moderate selectivity for BGT-1. Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice.

GABA Uptake Related Products: NNC 711 SKF 89976A CI 966

Toll-like receptor 7 (TLR7) agonist
RWJ 21757
Induces immune cell activation and increases cytokine production. Displays antitumour and antiviral activity in various animal models.
TLR7 Related Products: Caffeic acid phenethyl ester IMD 0354 IKK 16

Find all NEW products in your research area.

Other new products this month : L-817,818, SQ 22536, Probucol, ROS 234, Nefadozone, Caffeine, Progesterone, β-Estradiol, Theophylline, SNAP 5089, Quinelorane, NNC 05-2090, MRS 1754, 17-PA, RWJ 21757, TC 2559, Acetylcholine chloride

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