Neurochemicals
|
Signal Transduction Agents
|
Peptides
|
Biochemicals
High Performance Life Science Reagents
New Products for August 2007
Highly selective CB
2
agonist
Gp 1a
CB
2
receptor agonist that displays > 9800-fold selectivity over CB
1
receptors. Increases P-ERK1/2 expression in HL-60 cells in vitro.
CB
2
Related Products:
L-759,633
L-759,656
CB 65
Potent and selective CXCR2 antagonist
SB 225002
CXCR2 chemokine receptor antagonist (IC
50
= 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GROα-mediated calcium mobilisation in HL60 cells (IC
50
values are 8 and 10 nM respectively).
CXCR2 Related Products:
ZK 756326
RS 504393
DAPTA
Potent and selective P2Y
6
agonist
3-Phenacyl UDP disodium salt
Potent and selective P2Y
6
receptor agonist (EC
50
values are 7, > 1000 and > 10000 nM for P2Y
6
, P2Y
2
and P2Y
4
receptors respectively).
P2Y
6
Related Products:
MRS 2578
Selective AMPA antagonist
YM 90K hydrochloride
Displays 26-fold and > 440-fold selectivity over kainate and NMDA receptors respectively. Neuroprotective; delays neuronal death in a global ischaemia model and cerebral infarction in a focal ischaemia model.
AMPA Related Products:
ZK 200775
GYKI 52466
Potent and selective VPAC
2
agonist
Bay 55-9837
Selective VPAC
2
receptor agonist (IC
50
values are 60, 8700 and > 10000 nM for VPAC
2
, VPAC
1
and PAC
1
receptors respectively). Stimulates glucose-dependent insulin secretion in isolated human pancreatic islets.
VPAC
2
Related Products:
[Ala
11,22,28
]VIP
Find all
NEW products
in your research area.
Home
|
About Tocris
|
Company History
|
Search Catalog
|
Contact
|
Site Map
Unique Range
A broad collection of high performance reagents
Unrivalled Quality
Certified high purity
Next Day Delivery
Fast service guaranteed
Expert service
Specialist technical support
New Product Guide
Request your copy
Search for Products
Request Poster
Request Catalog
Suggest New Product
Contact Us