| Neurochemicals | Signal Transduction Agents | Peptides | Biochemicals | |
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High Performance Life Science Reagents |
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New Products for January 2008
Selective, non-peptide CRF1 antagonist
CP 154526 Blocks CRF-induced adenylate cyclase activation (Ki = 3.7 nM) and attenuates activation of the HPA axis by CRF. Displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant. CRF Related Products: NBI 27914 K 41498 Stressin 1
Selective 5-HT7 antagonist
SB 258719 Displays > 100-fold selectivity over a range of other receptors. Reverses the hypothermic effect of 5-CT in mice following i.p. administration. 5-HT Related Products: LP 44 SB 269970 AS 19
TRPM8 agonist; cooling agent
WS 3 Cooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM). TRP Receptor Related Products: Icilin AMG 9810 SB 366791
5-HT3 antagonist
Granisetron Possesses potent antiemetic activity. 5-HT Related Products: Tropisetron SR 57227 Y-25130
Orally active, subtype-selective NR1A/NR2B antagonist
TCS 46b IC50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively. NMDA Related Products: Ro 25-6981 Ro 04-5595 CCMQ
Find all NEW products in your research area.
Other new products this month :
Arachidonyl Serotonin,
CI 988,
Flupirtine,
Iloprost,
ONO 4817,
PAF (C16),
PD 176252,
PD 135158,
Taltirelin,
U 89843A,
U 92016A,
[Arg8]-Vasopressin,
[Lys8]-Vasopressin,
Withaferin A
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