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Home »
Pharmacology » 7-TM Receptors » Glutamate (Metabotropic) Receptors » Glutamate (Metabotropic) Group I Receptors » DCB
DCBCat No. 1952 |
Price and Availability |
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Alternative Name: 3,3'-Dichlorobenzaldazine Chemical Name: [(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehy de |
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Biological Activity
Allosteric ligand for the metabotropic glutamate receptor mGlu5; displays neutral modulation. Does not affect agonist-stimulated mGlu5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB (Cat. No. 1625) and DMeOB (Cat. No. 1953).Technical Data
M.Wt:277.15
Formula:C14H10Cl2N2
Solubility:Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity: >98 %
Storage:Desiccate at RT
CAS No:[6971-97-7]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
O'Brien et al (2003) A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5. Mol.Pharmacol. 64 731.If you know of a useful citation for this product please let us know.
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Keywords: DCB, Allosteric, modulators, mGlu5, mGluR5, Group, I, Receptors, Glutamate, Metabotropic
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