PKA inhibitor fragment (6-22) amide
Cat. No. 1904
Alternative Names: Protein kinase inhibitor-(6-22)-amide, PKI-(6-22)-amide
Biological ActivityPotent inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM); derived from the active portion of the heat-stable PKA inhibitor protein PKI.
(Modifications: Ile-17 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Glass et al (1989) Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J.Biol.Chem. 264 8802. PMID: 2722799.
Glass et al (1989) Protein kinase inhibitor-(6-22)-amide peptide analogs with standard and nonstandard amino acid substitutions for phenylalanine 10. J.Biol.Chem. 264 14579. PMID: 2760075.
Otmakhova et al (2000) Inhibition of the cAMP pathway decreases early long-term potentiation at CA1 hippocampal synapses. J.Neurosci. 20 4446. PMID: 10844013.
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Keywords: PKA Inhibitor Fragment (6-22) amide, supplier, Potent, protein, kinases, A, inhibitors, PKA
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