Cat. No. 1898
Biological ActivityEndogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.
(Modifications: Cys-15 = C-terminal OH, Disulfide Bridge between 4 - 2, 7 - 5)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Currie et al (1992) Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc.Natl.Acad.Sci.U.S.A. 89 947. PMID: 1346555.
Nokihara et al (1997) Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. Regul.Pept. 70 111. PMID: 9272623.
Beltowski (2001) Guanylin and related peptides. J.Physiol.Pharmacol. 52 351. PMID: 11596856.
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Keywords: Guanylin (human), supplier, Endogenous, activators, intestinal, guanylyl, cyclase, sGC, Guanylyl, cyclases
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March 28 - April 1, 2015