R&D Systems Inc. Tocris Bioscience Boston Biochem

Guanylin (human)

Cat. No. 1898

Guanylin (human) Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bridges: 4 -2*, 7 - 5*)

Price and Availability

For Guanylin (human) pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Biological Activity

Endogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.

Technical Data

M.Wt:
1458.65
Formula:
C58H87N15O21S4
Sequence:
PGTCEICAYAACTGC

(Modifications: Cys-15 = C-terminal OH, Disulfide Bridge between 4 - 2, 7 - 5)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
183200-12-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Currie et al (1992) Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc.Natl.Acad.Sci.U.S.A. 89 947. PMID: 1346555.

Nokihara et al (1997) Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. Regul.Pept. 70 111. PMID: 9272623.

Beltowski (2001) Guanylin and related peptides. J.Physiol.Pharmacol. 52 351. PMID: 11596856.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Guanylin (human), supplier, Endogenous, activators, intestinal, guanylyl, cyclase, sGC, Guanylyl, cyclases

Quick Order

Find multiple products by catalog number

divider line

New Product E-alerts

Sign up for email updates from Tocris

Sign-up for New Product E-alerts

Enter your email address below to sign up to receive our email updates:

divider line

Bio-Techne Events

2014 ASCB/IFCB meeting

ASCB/IFCB 2014

December 6 - 10, 2014

Philadelphia, USA

Booth Number: 515