Cat. No. 1860
Chemical Name: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
Biological Activity5-HT1 and 5-HT2C receptor partial agonist (Ki values are 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Miczek et al (1989) Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor subtypes. Psychopharmacol.Bull. 25 399. PMID: 2483273.
Schipper et al (1990) Neurochemical profile of eltoprazine. Drug Metabol.Drug Interact. 8 85. PMID: 1982626.
Gommans et al (1997) Discriminative stimulus properties of eltoprazine. Life Sci. 61 11. PMID: 9200664.
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Keywords: Eltoprazine hydrochloride, supplier, 5-HT2C, receptor, partial, agonists, 5-HT1, Serotonin, Receptors
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