JWH 133 (in Tocrisolve™ 100)
Cat. No. 1783
Chemical Name: (6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
Biological ActivityPotent CB2 selective agonist (Ki = 3.4 nM), in water-soluble emulsion (for details see TocrisolveTM 100 Cat. No. 1684). Approx. 200-fold selective over CB1 receptors. Active in vivo, reducing spasticity in a murine model of multiple sclerosis. JWH 133 also available as a solid (Cat. No. 1343).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Huffman et al (1999) 3-(1'-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorg.Med.Chem. 7 2905. PMID: 10658595.
Pertwee (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635. PMID: 10469884.
Baker et al (2000) Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 404 84. PMID: 10716447.
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Keywords: JWH 133 (in Tocrisolve 100), supplier, Potent, selective, CB2, agonists, water-soluble, emulsion, cannabinoids, Receptors, JWH133, cb2r
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October 15, 2013