Autocamtide-2-related inhibitory peptide
Cat. No. 1688
Alternative Name: AIP
Biological ActivitySelective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor (IC50 = 40 nM). Selective over PKC, PKA and CaM kinase IV (IC50 > 10 μM).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Ishida et al (1995) A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem.Biophys.Res.Commun. 212 806. PMID: 7626114.
Ishida and Fujisawa (1995) Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain. J.Biol.Chem. 270 2163. PMID: 7836445.
Takasawa et al (1995) Requirement of calmodulin-dependent protein kinase II in cyclic ADP-ribose-mediated intracellular Ca2+ mobilization. J.Biol.Chem. 270 30257. PMID: 8530441.
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Keywords: Autocamtide-2-related inhibitory peptide, supplier, Selective, CaM, kinase, II, inhibitors, Calmodulin-Activated, calmodulin-dependent, Protein, Kinases, Ca2+, Binding, modulators, Calcium, Signaling, Signalling