Cat. No. 3002
Chemical Name: 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
Biological ActivityAntioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid peroxidation and blocks glutamate neurotoxicity in vitro and in vivo. Inhibits apoptosis of astrocytes via increased NGF production.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Zs-Nagy (1990) Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review. Arch.Gerontol.Geriatr. 11 177. PMID: 15374467.
Civenni et al (1999) Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes. Eur.J.Pharmacol. 370 161. PMID: 10323265.
Takuma et al (2000) CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production. Eur.J.Pharmacol. 406 333. PMID: 11040339.
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Keywords: Idebenone, supplier, Antioxidant, neuroprotective, agent
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October 15, 2013