Apelin-17 (human, bovine)

Cat. No. 3007

Apelin-17 (human, bovine) Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

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Alternative Names: K17F, Prepro-61-77-Apelin

Biological Activity

Endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).

Technical Data

M.Wt:
2138.56
Formula:
C96H156N34O20S
Sequence:
KFRRQRPRLSHKGPMPF
Solubility:
Soluble to 1.20 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
217082-57-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Tatemoto et al (1998) Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem.Biophys.Res.Comms. 251 471.

Medhurst et al (2003) Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J.Neurochem. 84 1162. PMID: 12603839.

De Mota et al (2004) Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release. Proc.Natl.Acad.Sci. USA 101 10464.

If you know of a relevant citation for this product please let us know.

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Keywords: Apelin-17 (human, bovine), supplier, Endogenous, APJ, receptor, agonists, Receptors, Apelin, adipokines, Tocris Bioscience, Apelin Receptor Agonists

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