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[Des-octanoyl]-Ghrelin (rat)

Cat No. 2951

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Alternative Name: Des-acyl ghrelin (rat)

Biological Activity

Non-acylated, major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growth hormone release.

Technical Data

M.Wt:

3188.63

Formula:

C₁₃₉H₂₃₁N₄₅O₄₁

Sequence:

GSSFLSPEHQKAQQRKESKKPPAKLQPR

Storage:

Desiccate at -20°C

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Resources

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch

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Material Safety Data Sheet: View current batch

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References

Bedendi et al (2003) Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln¹⁴-ghrelin. Eur.J.Pharmacol. 476 87. Thompson et al (2004) Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor. Endocrinology 145 234. Cassoni et al (2004) Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines. Eur.J.Endocrinol. 150 173.

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Keywords: [des-octanoyl]-Ghrelin (rat), circulating, ghrelin, devoid, activity, GHS-R1a, Receptors, Growth, Hormone, Secretagogue, Receptor, 1a, Ghrelin

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