Cat. No. 2715
Alternative Name: 3-Phenacyl UDP disodium salt
Chemical Name: 3-(2-Oxo-2-phenylethyl)-uridine-5'-d
Biological ActivityPotent and selective P2Y6 receptor agonist (EC50 values are 70, > 1000 and > 10000 nM for P2Y6, P2Y2 and P2Y4 receptors respectively). Induces contractions of rat isolated intrapulmonary arteries in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
El-Tayeb et al (2006) Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4 and P2Y6 receptors. J.Med.Chem. 49 7076. PMID: 17125260.
Mitchell et al (2012) Identification of contractile P2Y1, P2Y6, and P2Y12 receptors in rat intrapulmonary artery using selective ligands. J.Pharmacol.Exp.Ther. 343 755. PMID: 22991416.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: PSB 0474, supplier, Potent, selective, P2Y6, agonists, Receptors, Purinergic, purinoceptors, PSB0474
Find multiple products by catalog number
New Products in this Area
Potent Smo antagonistONO 8130
EP1 receptor antagonistTC-G 1008
Potent and selective GPR39 agonistRo 1138452 hydrochloride
Selective prostacyclin IP receptor antagonistJNJ 27141491
Potent and selective human CCR2 antagonistTY 52156
S1P3 receptor antagonistElinogrel
P2Y12 antagonistRactopamine hydrochloride
Trace amine 1 (TA1) receptor agonist
September 17, 2015