PSB 0474

Cat. No. 2715

PSB 0474 C17H18N2Na2O13P2 [917567-60-3]

Price and Availability

For PSB 0474 pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Name: 3-Phenacyl UDP disodium salt

Chemical Name: 3-(2-Oxo-2-phenylethyl)-uridine-5'-diphosphate disodium salt

Biological Activity

Potent and selective P2Y6 receptor agonist (EC50 values are 70, > 1000 and > 10000 nM for P2Y6, P2Y2 and P2Y4 receptors respectively). Induces contractions of rat isolated intrapulmonary arteries in vitro.

Technical Data

Soluble in water (supplied pre-dissolved at a concentration of 10mM)
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet


El-Tayeb et al (2006) Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4 and P2Y6 receptors. J.Med.Chem. 49 7076. PMID: 17125260.

Mitchell et al (2012) Identification of contractile P2Y1, P2Y6, and P2Y12 receptors in rat intrapulmonary artery using selective ligands. J.Pharmacol.Exp.Ther. 343 755. PMID: 22991416.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: PSB 0474, supplier, Potent, selective, P2Y6, agonists, Receptors, Purinergic, purinoceptors, PSB0474, Purinergic (P2Y) Receptor Agonists

Quick Order

Find multiple products by catalog number

divider line

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

Highlights over 250 products for cardiovascular research. Request copy or view PDF today.

divider line

Pain Research Product Guide

Pain Research Product Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

P2 Receptors Review

P2X and P2Y Receptors Scientific Review

Written by Kenneth Jacobson, an expert in the field. Request copy or view PDF today.

divider line

Regulation of Vascular Reactivity by GPCRs

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Life Science Poster

'Regulation of Vascular Reactivity by G-protein-coupled Receptors' summarizes the key GPCRs regulating vascular reactivity. Request copy today.

divider line

New Products in this Area

MRS 2905

Potent and selective P2Y14 receptor agonist


Potent prostacyclin (PGI2) analog

S 18886

Potent thromboxane A2 (TP) antagonist


Potent Smo antagonist

ONO 8130

EP1 receptor antagonist

TC-G 1008

Potent and selective GPR39 agonist

Ro 1138452 hydrochloride

Selective prostacyclin IP receptor antagonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Pharmacology 2015

Pharmacology 2015

December 15 - 17, 2015

London UK