Home » Research Area » » Ion Channels » Potassium Channels » Calcium-Activated Potassium (K_Ca) Channels » UCL 2077

UCL 2077

Cat. No. 2661

Price and Availability

For UCL 2077 pricing & availability please select your country from the drop down menu:
Submit

By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N-Trityl-3-pyridinemethanamine

Biological Activity

Slow afterhyperpolarization (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca²⁺ currents or the time course of sAHP/sI_AHP.

Technical Data

M.Wt:

350.46

Formula:

C₂₅H₂₂N₂

Solubility:

Soluble to 50 mM in DMSO and to 25 mM in ethanol

Purity:

>99 %

Storage:

Store at RT

CAS No:

918311-87-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Shah et al (2006) Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077). Mol.Pharmacol. 70 1494. PMID: 16877678.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Calcium-Activated Potassium (K_Ca) Channels

Potassium Channels

Keywords: UCL 2077, supplier, Slow, hyperpolarization, sAHP, channels, blockers, Potassium, KCa, Channels, ca2+-activated, ca2+-dependent, K+, UCL2077