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Compound WCat. No. 2654 |
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Alternative Name: CW Chemical Name: 3,5-Bis(4-nitrophenoxy)benzoic acid |
Biological Activity
Inhibitor of γ-secretase; causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).Certificate of Analysis / Safety Data Sheet
References
Okochi et al (2006) Secretion of the notch-1 Aβ-like peptide during notch signaling. J.Biol.Chem. 281 7890. PMID: 16434391.
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Keywords: Compound W, supplier, γ-secretase, gamma-secretase, inhibitors, reduces, Aβ4, β42, beta42, levels, Proteinases, Proteases, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, beta, Peptides, CompoundW
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