R&D Systems Inc. Tocris Bioscience Boston Biochem

Compound W

Cat. No. 2654

Compound W C19H12N2O8 [173550-33-9]

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Alternative Name: CW

Chemical Name: 3,5-Bis(4-nitrophenoxy)benzoic acid

Biological Activity

Inhibitor of γ-secretase; causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).

Technical Data

M.Wt:
396.31
Formula:
C19H12N2O8
Solubility:
Soluble to 50 mM in 1.1eq. NaOH and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
173550-33-9

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Okochi et al (2006) Secretion of the notch-1 Aβ-like peptide during notch signaling. J.Biol.Chem. 281 7890. PMID: 16434391.

If you know of a relevant citation for this product please let us know.

Keywords: Compound W, supplier, γ-secretase, gamma-secretase, inhibitors, reduces, Aβ4, β42, beta42, levels, Proteinases, Proteases, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, beta, Peptides, CompoundW

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