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Home »
Cellular Processes » Signal Transduction » Calcium Signaling » Calcium Binding Protein Modulators » STO-609 acetate
STO-609 acetateCat. No. 1551 |
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Chemical Name: 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate |
Biological Activity
Selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki values are 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK.Certificate of Analysis / Safety Data Sheet
Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet
References
Tokumitsu et al (2002) STO-609, a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase. J.Biol.Chem. 277 15813. PMID: 11867640.
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Keywords: STO-609 acetate, supplier, Selective, CaM, kinases, inhibitors, Ca2+, Binding, Protein, modulators, Calcium, Signaling, Signalling, Calmodulin-Activated
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