R&D Systems Inc. Tocris Bioscience Boston Biochem

Splitomicin

Cat. No. 1542

Splitomicin C13H10O2 [5690-03-9]

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Chemical Name: 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one

Biological Activity

Inhibitor of Sir2p (IC50 = 60 μM), an NAD+-dependent Sir2 family deacetylase required for chromatin-dependent silencing in yeast.

Technical Data

M.Wt:
198.22
Formula:
C13H10O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
5690-03-9

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Bedalov et al (2001) Identification of a small molecule inhibitor of Sir2p. Proc.Natl.Acad.Sci.U.S.A. 98 15113. PMID: 11752457.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Splitomicin, supplier, Sir2p, inhibitors, Sirtuin, Sir2-like, Family, Deacetylases

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