Cat. No. 1542
Chemical Name: 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
Biological ActivityInhibitor of Sir2p (IC50 = 60 μM), an NAD+-dependent Sir2 family deacetylase required for chromatin-dependent silencing in yeast.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Bedalov et al (2001) Identification of a small molecule inhibitor of Sir2p. Proc.Natl.Acad.Sci.U.S.A. 98 15113. PMID: 11752457.
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Keywords: Splitomicin, supplier, Sir2p, inhibitors, Sirtuin, Sir2-like, Family, Deacetylases
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