Cat. No. 1542
Chemical Name: 1,2-Dihydro-3H-naphtho[2,1-b]pyran-
Biological ActivityInhibitor of Sir2p (IC50 = 60 μM), an NAD+-dependent Sir2 family deacetylase required for chromatin-dependent silencing in yeast.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Bedalov et al (2001) Identification of a small molecule inhibitor of Sir2p. Proc.Natl.Acad.Sci.U.S.A. 98 15113. PMID: 11752457.
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Keywords: Splitomicin, supplier, Sir2p, inhibitors, Sirtuin, Sir2-like, Family, Deacetylases