R&D Systems Inc. Tocris Bioscience Boston Biochem

Clozapine N-oxide

Cat. No. 4936

Clozapine N-oxide C18H19ClN4O [34233-69-7]

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Chemical Name: 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine

Biological Activity

Metabolite of clozapine (Cat. No. 0444).

Technical Data

M.Wt:
342.82
Formula:
C18H19ClN4O
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
>98 %
Storage:
Store at RT
CAS No:
34233-69-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Other Information

  • This product contains 1 molar equivalent of ethanol.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Eiermann et al (1997) The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine. Br.J.Clin.Pharmacol. 44 439. PMID: 9384460.

Zhang et al (2007) Impaired microsomal oxidation of the atypical antipsychotic agent clozapine in hepatic steatosis. J.Pharmacol.Exp.Ther. 322 770. PMID: 17522342.

If you know of a relevant citation for this product please let us know.

Keywords: Clozapine N-oxide, supplier, clozapine, metabolite, 5HT2A/2C, non-selective, receptors, serotonin, 5HT2C, 5HT2, 5HT2A, dopaminergic, dopamine, antagonists, D4

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