Cat. No. 4583
Chemical Name: 4-[(3S,5R,8R,9S,10S,12R,13S,14S)-3-
Biological ActivityInhibits membrane-bound α-subunits of the Na+/K+ ATPase pump in myocytes. Increases RGS2 protein levels in primary vascular smooth muscle cells through an Na+/K+ ATPase pump-dependent mechanism.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Gheorghiade et al (2004) Digoxin in the management of cardiovascular disorders. Circulation 109 2959. PMID: 15210613.
Buckalew (2005) Endogenous digitalis-like factors. An historical overview. Front.Biosci. 10 2325. PMID: 15970498.
Sjogren et al (2012) Cardiotonic steroids stabilize regulator of g protein signaling 2 protein levels. Mol.Pharmacol. 82 500. PMID: 22695717.
If you know of a relevant citation for this product please let us know.
Keywords: Digoxin, supplier, cardiac, glycoside, digitalis, sodium, potassium, ATP, Na+, K+, ATPase, pump
Find multiple products by catalog number
New Products in this Area
Selective NHE1 inhibitor; cardioprotective and antitumorVU 0463271
Potent and selective inhibitor of the neuronal K-Cl cotransporter (KCC2)CLP 257
Selective KCC2 K+-Cl- cotransporter activator
September 5 - 8, 2015