R&D Systems Inc. Tocris Bioscience Boston Biochem

Phenobarbital sodium salt

Cat. No. 4578

Phenobarbital sodium salt C12H11N2NaO3 [57-30-7]

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Chemical Name: 5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-py­rimidinetrione sodium salt

Biological Activity

Enhances GABAergic activity. Long-acting barbiturate; slow-acting barbiturate (Cat. No. 4579) also available.

Technical Data

M.Wt:
254.22
Formula:
C12H11N2NaO3
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
57-30-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
Safety Data Sheet: View Safety Data Sheet

References

ffrench-Mullen et al (1993) Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current. J.Neurosci. 13 3211. PMID: 8101867.

Nardou et al (2011) Phenobarbital but not diazepam reduces AMPA/kainate receptor mediated currents and exerts opposite actions on initial seizures in the neonatal rat hippocampus. Front.Cell.Neurosci. 5 Epub. PMID: 21847371.

If you know of a relevant citation for this product please let us know.

Keywords: Phenobarbital sodium salt, supplier, Phenobarbital, barbiturates, anticonvulsants, GABAergic, GABA

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