Cat. No. 4513
Chemical Name: 2-[((1,1'-Biphenyl)-4-ylamino)carbonyl]benzoic acid
Biological ActivityPotently induces differentiation of human mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Reduces disease severity in a mouse model of osteoarthritis; displays protective effects against osteoarthritic stimuli in mature chondrocytes in vitro.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Johnson et al (2012) A stem cell-based approach to cartilage repair. Science 336 717. PMID: 22491093.
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Keywords: Kartogenin, supplier, Supplier, mesenchymal, stem, cell, differentiation, differentiators, potently, inducers, chondrocytes, cartilage, osteoarthritis
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