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KartogeninCat. No. 4513 |
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Chemical Name: 2-[((1,1'-Biphenyl)-4-ylamino)carbonyl]benzoic acid |
Biological Activity
Potently induces differentiation of human mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Reduces disease severity in a mouse model of osteoarthritis; displays protective effects against osteoarthritic stimuli in mature chondrocytes in vitro.Certificate of Analysis / Safety Data Sheet
References
Johnson et al (2012) A stem cell-based approach to cartilage repair. Science 336 717. PMID: 22491093.
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Keywords: Kartogenin, supplier, Supplier, mesenchymal, stem, cell, differentiation, differentiators, potently, inducers, chondrocytes, cartilage, osteoarthritis
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