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STF 31

Cat. No. 4484

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Chemical Name: 4-[[[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinylbenzamide

Biological Activity

Inhibitor of GLUT1; inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells. Activity causes necrotic cell death in von Hippel-Lindau (VHL)-deficient RCC cells.

Technical Data

M.Wt:

423.53

Formula:

C₂₃H₂₅N₃O₃S

Solubility:

Soluble to 100 mM in DMSO

Purity:

>99 %

Storage:

Store at RT

CAS No:

724741-75-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Chan et al (2011) Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Sci.Transl.Med. 3 94ra70. PMID: 21813754.

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