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PSB 1114

Cat. No. 4333

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Chemical Name: 4-Thiouridine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt

Biological Activity

Potent, selective P2Y₂ agonist (EC₅₀ = 0.134 μM). Displays >60-fold selectivity versus P2Y₄ and P2Y₆ receptors.

Technical Data

M.Wt:

622.14

Formula:

C₁₀H₁₁F₂N₂Na₄O₁₃P₃S

Solubility:

Soluble in water (supplied pre-dissolved at a concentration of 10mM)

Purity:

>98 %

Storage:

Store at -20°C

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

El-Tayeb et al (2011) Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y₂, P2Y₄, and P2Y₆ receptors. J.Med.Chem. 54 2878. PMID: 1417463.

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