Cat. No. 4308
Chemical Name: (1R)-2,3-Dihydro-N-2-propynyl-1H-in
Biological ActivitySelective irreversible MAO-B inhibitor. Displays antiParkinsonian activity; exhibits neuroprotective and antiapoptotic activity against several neurotoxins in cell culture.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Finberg and Youdim (2002) Pharmacological properties of the anti-Parkinson drug rasagiline; modification of endogenous brain amines, reserpine reversal, serotonergic and dopaminergic behaviours. Neuropharmacology 43 1110. PMID: 12504917.
Maruyama et al (2002) The anti-parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells. J.Neural Transm. 109 467. PMID: 11956966.
Youdim and Weinstock (2002) Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]. Cell.Mol.Neurobiol. 21 555.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Rasagiline mesylate, supplier, Rasagiline, mesylate, monoamine, oxidases, mao-b, mao, b, inhibitors, selective, antiparkinsons, antiparkinsonian, parkinson's, parkinsons
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.