CP 775146

Cat. No. 4190

CP 775146 C26H33NO4 [702680-17-9]

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Chemical Name: 2-Methyl-2-[3-[(3S)-1-[2-[4-(1-methylethyl)phenyl]acetyl]-3-piperidinyl]phenoxy]-propanoic acid

Biological Activity

Selective, high affinity PPARα agonist (Ki values are 24.5 nM for PPARα and >10 μM for PPARβ and PPARγ in vitro). Exhibits hypolipidemic activity in vivo.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

M.Wt:
423.54
Formula:
C26H33NO4
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
702680-17-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Kane et al (2009) Molecular characterization of novel and selective peroxisome proliferator-activated receptor α agonists with robust hypolipidemic activity in vivo. Mol.Pharmacol. 75 296. PMID: 18971326.

If you know of a relevant citation for this product please let us know.

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Keywords: CP 775146, supplier, pfizer, CP775146, pparalpha, ppara, pparα, peroxisome, proliferator-activated, receptors, agonists, selective, hypolipidemic, hypolipidaemic

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